Her first two artists, Julian Schnabel and David Salle, became internationally known, and, in 1982, she was featured in a cover story on New York magazine tagged: "The New Queen of the Art Scene".
[7][8] Boone met sculptor Lynda Benglis at Hunter College and the artist introduced her to the director of Bykert Gallery, Klaus Kertess, where she would eventually work.
The gallery quickly rose to prominence by exhibiting new painters associated with neo-expressionism such as Eric Fischl, Julian Schnabel, and David Salle.
[10][11] Boone's gallery and presence throughout the 1980s offered a departure from conceptual and minimal approaches to art by supporting a revival in painting.
[13] A New York Times critic later described her gallery's 1979 exhibition of Julian Schnabel's work as perhaps being "the key launching pad" for neo-expressionism.
[30] In a statement to ArtNews, Boone said "If I'm going to be the Martha Stewart of the art world, I would hope to do it with the same humility, humor, grace and intelligence that she did.
[32] Boone was portrayed by Parker Posey in Julian Schnabel's 1996 biographical drama Basquiat,[6] accompanied by Dennis Hopper as Bischofberger.