She wrote extensively for magazines and for the public press, and was also the author of many dramas, lyric poems, operettas, stories for the young, and essays.

In addition to the operettas, "Just Like Cinderella" and "Jack Frost's Visit to the Fairies", her works included "Effle, Fairy Queen of Dolls," "Prince Pussin-Boots," "Golden Hair and her Knight of the Beanstalk in the Enchanted Forest," "Obed Owler and the Prize Writers," "How I Came to Leave Town and What Came of It," "Edith Morton, the Sensible Young Lady;" "The Story that the Willow Basket Told to Faith Fairchild;" "English Lyrics;" and "Home;" as well as a number of songs, such as "Were it not for Dreams;" ; "Twittering Swallow;" "Robin, Robin, Bold and Free;" "Down by the River;" "Not to Blame;" and "Our-Leafed Clover."

[2] Clarke spent her early years on her father's homestead, a portion of the Mount Hope lands obtained from King Philip, the chief of the Wampanoag.

[1] During her husband's four years of service as surgeon and surgeon-in-chief of brigade and of division of cavalry in the war, she took an active interest in work for the success of the Union cause.

"[1] The titles of some of her works included: "Effle, Fairy Queen of Dolls," for which she received the prize awarded by The Cambridge Tribune in 1880; "Prince Pussin-Boots," "Golden Hair and her Knight of the Beanstalk in the Enchanted Forest," "Obed Owler and the Prize Writers," "How I Came to Leave Town and What Came of It," "Edith Morton, the Sensible Young Lady;" "The Story that the Willow Basket Told to Faith Fairchild;" "English Lyrics;" and "Home."

[2] She traveled extensively, and accompanied her family on an extended tour through the British Isles and also through central and southern Europe, visiting all the capitals of those countries, for observation, study and for general self-improvement.

He was a member of the International Medical Congresses held in Washington, D.C., 1887; Berlin, 1890; Rome, 1894; Moscow, 1897 (honorary president, obstetrics and gynecology section in latter); Paris, 1900; Madrid, 1903; and Lisbon, 1906.