[7] In her subsequent return to private practice she represented criminal defendants including Les Wexner, an associate of Jeffrey Epstein,[8] and the Sackler family, owners of opioid manufacturer Purdue Pharma.

She is noted for having led the prosecution of John Gotti and overseen those of the terrorists responsible for the 1993 World Trade Center bombing, chief among them Sheik Omar Abdel Rahman and Ramzi Yousef.

[2] For 10 years, she was chair of the litigation department at Debevoise & Plimpton,[10] whose self-proclaimed "core practices" and expertise are focused on the success of Wall Street financial firms.

[18] In an October 2013 speech, White announced a new SEC enforcement tactic practiced by neighborhood beat police to root out petty crime.

[22] On June 2, 2015, Senator Elizabeth Warren wrote a letter to White indicating that her "leadership of the Commission has been extremely disappointing"[23] pointing out numerous shortcomings and failures during her tenure.

Warren admonished that White failed to finalize certain Dodd–Frank rules, did not curb the use of waivers for companies that violated securities laws, allowed settlements without admission of guilt, and was too frequently recused because of her husband's activities.

[26] On October 14, 2016, Senator Warren sent a formal written request to President Obama asking for the immediate dismissal of White as Chair of the SEC because of her refusal to develop public disclosure rules of political contributions made by corporations.

[28] In that same year, White was a member of a National Football League's external expert advisory panel on domestic violence, reviewing allegations against Ezekiel Elliott.

[36] White continued to represent Purdue Pharma after this, advocating for a settlement in bankruptcy court that would have absolved the Sackler Family of any criminal liability from their role in the opioid epidemic.

[39] In 2022, the National Football League confirmed that White had been hired to investigate allegations of misconduct and financial impropriety against Washington Commanders owner Dan Snyder.