Many of reggaeton's biggest names were featured in the album, such as Daddy Yankee, Wisin & Yandel, Zion & Lennox, Tito "El Bambino", Ivy Queen, Hector "El Father", Voltio, and many others.

It also featured some artists from outside the reggaeton genre, such as Frankie J, Cultura Profetica, Deevani, Tony Tun-Tun, Spliff Star, among others.

[2] Mas Flow 2 won the Lo Nuestro Award for Urban Album of the Year.

[3] Mas Flow 2 is one of the few reggaeton albums to sell over a million copies worldwide and remains as the most successful compilation in the genre's history.

[4] The sound introduced in the albums Mas Flow 1 and Mas Flow 2 is noted for inspiring the modern day sound of the reggaeton genre in the music of artists such as J Balvin, Nicky Jam, Farruko and Anuel AA.