Masatoshi Takeichi

[1] He shared the 2005 Japan Prize with Erkki Ruoslahti for "fundamental contribution in elucidating the molecular mechanisms of cell adhesion".

[3] In 1977 Takeichi discovered cadherin, and since then he has contributed to clarify its functions in tissue construction and to understand the molecular mechanisms of cell adhesion.

[1] Takeichi knew there was calcium dependent molecule that served an important role, but he had to find it.

He accurately hypothesized that the adhesions dependent on calcium played a role in managing cells' morphogenetic behavior.

His discovery of the cadherin family led to a developing field of studying adhesions pathways.

[1] Takeichi, along with other scientists, studied the mechanism behind hemagglutinin from Botulism and its effect on the epithelial barrier of the intestines.