The 250F principally used the SSG, 220 bhp (at 7400rpm) 2,493 cc (152.1 cu in) capacity 84 mm × 75 mm (3.31 in × 2.95 in) Maserati A6 straight-six engine, ribbed 13.4" drum brakes, wishbone independent front suspension, a De Dion tube axle, Borrani 16" & 17" wheels and Pirelli Stella Bianca tyres.

A streamlined version with bodywork which partially enclosed the wheels (similar to the 1954 Mercedes-Benz W196 "Typ Monza") was used in the 1956 French Grand Prix.

[1] The 250F first raced in the 1954 Argentine Grand Prix where Juan Manuel Fangio won the first of his two victories before he left for the new Mercedes-Benz team.

It was later developed into the 3 litre V12 that won two races powering the Cooper T81 and T86 from 1966 to 1969,[2] the final "Tipo 10" variant of the engine having three valves and two spark plugs per cylinder.

However, the car remained a favourite with the privateers, including Maria Teresa de Filippis, and was used by back markers through the 1960 F1 season, the last for the 2.5 litre formula.