The Mason City Micropolitan Statistical Area, as defined by the United States Census Bureau, is an area consisting of two counties in north central Iowa, anchored by the city of Mason City.

As of the census[2] of 2000, there were 54,356 people, 22,652 households, and 14,664 families residing within the μSA.

The racial makeup of the μSA was 96.57% White, 0.73% African American, 0.16% Native American, 0.62% Asian, 0.02% Pacific Islander, 0.81% from other races, and 1.10% from two or more races.

Hispanic or Latino of any race were 2.60% of the population.

Males had a median income of $29,859 versus $21,339 for females.