The Mason family of Virginia is a historically significant American political family of English origin, whose prominent members are known for their accomplishments in politics, business, and the military.

Along with James Madison, George Mason IV is known as the "Father of the Bill of Rights.

Thomson Mason's son, Stevens Thomson Mason (1760–1803)[14][15] served as a colonel in the Continental Army during the American Revolutionary War, a member of the Virginia state legislature, and as a Republican U.S.

[15] Thomson Mason's grandson John Thomson Mason (1787–1850)[15][17][18][19] was a lawyer, United States marshal, Secretary of Michigan Territory from 1830 through 1831,[15] land agent, and an important figure in the Texas Revolution.

George Mason IV's grandson James Murray Mason (1798–1871)[15][22] was a United States Representative and United States Senator from Virginia and represented the Confederate States of America as appointed commissioner of the Confederacy to Great Britain and France between 1861 and 1865 during the American Civil War.