Masontown is a borough in Fayette County, Pennsylvania, United States.

He later moved to Ohio and is buried on a family farm in Columbiana County.

[4] The borough's western border is the Monongahela River, which forms the Greene County line, but the main settled part of the borough is 1 mile (1.6 km) east of and 200 feet (60 m) higher than the river.

Pennsylvania Route 21 passes through the northern and western part of the borough, leading east 12 miles (19 km) to Uniontown, the Fayette county seat, and west across the Monongahela 16 miles (26 km) to Waynesburg.

Pennsylvania Route 166 passes through the center of Masontown as Main Street and leads south 10 miles (16 km) to Point Marion at the confluence of the Monongahela and Cheat rivers.