Mata Khan District (Pashto: متا خان ولسوالۍ, Persian: ولسوالی متاخان) is a district of Paktika Province, Afghanistan.

The district is within the heartland of the Andar tribe of Ghilji Pashtuns.

[1] The estimated population in 2019 was 26,720.

[2] Mata Khan District is located in the northern part of Paktika province, bordering Paktia's Zurmat District and Ghazni's Andar District.

This Paktika Province, Afghanistan location article is a stub.