Matchi-Manitou is an unorganized territory in the Abitibi-Témiscamingue region of Quebec, Canada.

It is one of five unorganized territories in La Vallée-de-l'Or Regional County Municipality.

Until July 6, 1996, Matchi-Manitou was a vast unorganized territory encompassing a land area of 16,760 km2 (6,470 sq mi).

It is named after Matchi-Manitou Lake (48°00′45″N 77°02′56″W / 48.01250°N 77.04889°W / 48.01250; -77.04889),[4] which used to be within its limits, but since 1996 is part of Senneterre and Val-d'Or.

Its name is taken from both the Cree and Innu languages and means "evil spirit".