He is arguably best known for his career at PSV, earning numerous awards and worldwide recognition as having the potential to be one of the greatest strikers of his generation, being named Dutch Footballer of the Year in 2003.

[4] Internationally, Kežman represented FR Yugoslavia / Serbia and Montenegro in one European Championship and one World Cup.

After finishing his professional playing career, Kežman became a sports agent,[5] currently representing Sergej Milinković-Savić among other players.

In that season, he drew attention to himself when, in the 111-th Eternal derby against Red Star, he scored a goal in the last minute, which gave Partizan a 2–1 victory.

The first goal came on 4 December 2004 in a 4–0 victory over Newcastle United at home, with an injury time penalty after coming on as a substitute in the 61st minute.

Kežman scored a goal in the 3rd round of that season's FA Cup against Scunthorpe United as Chelsea won 3–1 at home.

His attack down the right wing set up Chelsea's first goal in the 4-2 win against Barcelona in the Champions League Round of 16, in a "brilliant" play with the scorer Eiður Guðjohnsen.

In the 2007–08 UEFA Champions League, he appeared in over half of Fenerbahçe's group stage matches against the likes of his former club PSV, Internazionale and CSKA Moscow.

Ironically, he even played against Chelsea over both legs of the 2008 Champions League quarter-finals; the first of which he started and showed off with a close bicycle kick in a 2–1 win,[19] while in the second leg he was subbed in during the dying minutes of his team's 2–0 loss at Stamford Bridge, where Fenerbahçe was eliminated in the longest-lasting Champions League campaign in the club's history.

As a result of this and the preceding regular season, in which Kežman scored almost a goal every other game by statistical average, Fenerbahçe S.K.

On 30 August 2009, it was announced that Kežman would be joining Zenit Saint Petersburg from Paris Saint-Germain on a season-long loan, with a purchase option for an undisclosed fee.

[24][25][26] On 20 January 2011, it was announced that Kežman had signed to play for South China for the rest of the 2010–11 Hong Kong First Division League.

[27][28] Kežman made his debut on 29 January 2011 versus NT Realty Wofoo Tai Po which lost 1–0; he was substituted by Leung Chun Pong in the 64th minute.

[32] In the final match of the 2010–11 Hong Kong FA Cup, Kežman managed to take advantage of an opponent's defensive error and scored an outstanding goal in extra time to give his team a 2–1 win over NT Realty Wofoo Tai Po on 29 May 2011.

[33] On 31 August 2011, Kežman joined Belarusian side BATE Borisov as a free agent until the end of the year.

[34] He was seen as a reinforcement for upcoming UEFA Champions League group stage games and as a potential replacement for seriously injured striker Vitali Rodionov.

[35][36] Kežman marked his senior international debut for FR Yugoslavia during March 2000 with a goal against China in a friendly match as part of the preparations for UEFA Euro 2000.

Despite being the fourth attacking option behind Predrag Mijatović, Savo Milošević and Darko Kovačević, 21-year-old Kežman got his chance as substitute late in the group match versus Norway.

In February 2003, after embarrassing performances of the team during UEFA Euro 2004 qualifying, Kežman announced that he retired from the national jersey.

After his sending off against Argentina at the 2006 FIFA World Cup, Kežman did not receive any call up for his country's national team.