[1] From there he moved to Guadalajara, in the service for six years of the Duke, Diego Hurtado de Mendoza.
From 1544 to 1548 he lived in the castle at Arévalo as teacher of the Infantas Maria and Joanna, daughters of Charles V, Holy Roman Emperor (1500-1558).
Toward the end of his life Mateo Flecha became a monk of the Cistercian Order, living in the Monastery at Poblet, where he died in 1553.
The majority of his works can be found in the Cancionero of the Duke of Calabria (Venice, 1556), also known as the “Cancionero de Uppsala.” Flecha is best known as composer of the "ensalada" (literally "salad"), a work for four or five voices written for the diversion of courtiers in the palace.
The ensalada frequently mixed languages: Spanish, Catalan, Italian, French, and Latin.