Mathías Calfani (born January 21, 1992) is an Uruguayan professional basketball player.

Standing at 2.04 m (6' 81⁄2)" tall,[1] he plays at the power forward and center positions.

[2] In his pro club career, Calfani has played in both the South American 2nd-tier level FIBA South American League, and the South American 1st-tier level FIBA Americas League.

Calfani averaged 10 points, 5 rebounds, 2 assist and 2 steals per game, shooting 57% from the field.

[4] Calfani is a member of the senior Uruguayan national basketball team.