Mathias Ntawulikura (born 14 June 1964 in Gisovu/Karongi) is a retired Rwandan long-distance runner.
He also participated five times in the IAAF World Cross Country Championships.
He was forty when he competed in the marathon at the 2004 Athens Olympics; of the hundred men who started the race, he came 62nd with a time of 2hours, 26 minutes, 5 seconds.
In 2004, Ntawulikura joined three other track and field athletes - Nigerian Mary Onyali, Mozambican Maria Mutola, and Angolan João N'Tyamba in becoming the second African to compete at five Olympics.
He was affiliated with the Pro Patria Milano sporting club in Italy.