Mathira was born into a Muslim family in Harare, Zimbabwe to a South African father and a Pakistani mother.

[4] She made her debut in music videos of Jadugar, Desi Beat and "Nachdi Kamal" by Malkoo and Woh Kaun Thi by Rizwan-ul-Haq, and "Jotha Tu Hai" by Arbaz Khan.

In 2013, she made her debut in Bollywood by doing an item song "Lakk Ch Current" in Indian Punjabi film Young Malang.

[6] She has also done an item number "Masti Mein Doobi Raat Hai" in the film Main Hoon Shahid Afridi starring Humayun Saeed.

[7] She then appeared in the music video of the song "Jhootha" with young rapper Arbaz Khan, which was released on 30 December 2013.