Best known for his large paintings depicting historical scenes, and his series of colourful landscapes and seascapes of his native Dalmatia, Medović is one of the earliest modern Croatian painters.

Medović then moved to Zagreb and joined a group of artists led by Vlaho Bukovac, a renowned painter.

Since 1901 Medović increasingly began to spend time on his native Pelješac in southern Croatia, painting nature, still lifes, seascapes and landscapes in a style marked by his use of colour and light shadows.

[2] However, the rigid and outdated artistic style did not suit Medović, and he looked for a different teacher in Giuseppe Grandi, then in the private school of Antonio Ciseri in Florence.

Dr Franjo Rački (a founder member of the Croatian Academy of Sciences and Arts) and Dr Iso Kršnjav (head of the Department of Culture (Croatian: odjela za kulturu)) invited him to Zagreb to join the group of artists around Vlaho Bukovac, a Dubrovnik artist who had recently left Paris and settled in Zagreb.

Medović also painted a series of portraits of Zagreb people using fragmented lines, soft contours and vibrant colours.

His subjects were taken from the nature around him, still lifes of fruit and fish, seascapes, and landscapes, filled with colour, light and soft shadows.

[1] During his time in Zagreb (1895–1907), Medović gradually absorbed some of Bukovac's techniques and brighter colours into his own artistic personality.

His palette became lighter and brighter as he worked outdoors: browns, greys and dull greens became purer, and were joined the purple of heather, the yellow of broom, and the rich array of blues of the sea.

With thick impasto and impulsive brush strokes, around 1907 a new style emerged in his work – pointillism in a light, bright colours, that he used for his landscapes of Pelješac.

However, his major contribution to Croatian painting is his series of landscapes, full of bright southern light and vigorous colours.