Aside from a successful solo career, Matsuura (nicknamed Ayaya), also did numerous collaborations with other members of Hello!

Matsuura starred in the Japanese film Sukeban Deka: Codename = Asamiya Saki (known internationally as Yo-Yo Girl Cop) opposite Rika Ishikawa, released on September 30, 2006.

[2] Following the cancellation of the two concerts, Matsuura's management confirmed the rumours, reported the young idol had been taking painkillers to continue working and scheduled a press conference to discuss her condition.

[3][4] On the following day Matsuura made a public statement on PBS apologizing to her fans and expressing her desire to get back to her singing career as soon as possible.

Since her press conference, Matsuura returned to her normal hosting duties on her weekly radio show, "Matsuura Aya no All Night Nippon" and returned to singing in a limited capacity, as demonstrated on her appearance on Hey!

On March 8, 2008, Matsuura—as a secret guest—performed at the opening ceremony of the Fourth Special Olympics Japan Winter National Games, a national event in preparation of the 2009 Special Olympics World Winter Games held in Boise, Idaho.

Project on March 31, 2009, but months later, on August 26, 2009, Matsuura launched her own blog called Ayablog and announced that her Omoi Afurete tour will be her last for two or three years.

In late August 2011, it was revealed that she is diagnosed with endometriosis, which has been and will continue to limit her concert activities in the future.

[12] Matsuura has appeared in many commercials for various companies; notably Pretz snack foods, Epson color printers, and Kirin beverages.

She has also taken part and co-hosts the television show Utawara with other names in Japanese entertainment such as Johnny Jimusho's Jun Matsumoto.