He has appeared in comedy television roles in The IT Crowd, Garth Marenghi's Darkplace, The Mighty Boosh, Snuff Box, What We Do in the Shadows, Krapopolis, and Toast of London, the last of which he also co-created.

[9] After meeting Rich Fulcher while filming The Mighty Boosh, Berry wrote and starred in the comedy series Snuff Box with him on BBC Three.

[16][17] In 2010, Berry played journalist Michael Duffy in the BBC production Five Daughters, about events surrounding the Ipswich murders of 2006.

In each 15-minute episode, Berry explored the psyche of a guest patient, attempting to treat their problems in surreal dreamlike sequences.

He was briefly featured in the closing ceremony of the London 2012 Olympics, introducing ELO's "Mr. Blue Sky" by way of a mock weather forecast.

Notwithstanding mixed reviews, a series was commissioned, and the first episode was broadcast on 20 October 2013, and it brought Berry the 2015 BAFTA Award for Best Male Comedy Performance.

[26] Berry appeared in episode nine of the sixth season of Dan Harmon's television series Community, released on Yahoo Screen on 5 May 2015.

[27] Since 2019, Berry has starred in the FX TV adaptation of the film What We Do in the Shadows as Laszlo, one of four vampires living in Staten Island.

[33] Citing budget cuts caused by the COVID-19 pandemic, Channel 4 reversed their decision in January 2021, casting doubt on the show's future.

Layla Smith, chief executive of the show's production company OMG, said "Year of the Rabbit is a victim of the devastating effects of COVID.

The show was a six-part television programme for BBC One, broadcast under the title Toast of Tinseltown and co-written by Berry and Arthur Mathews.

That year, he also voiced the main villainess, The Butt Witch, in Twelve Forever, a series pilot created by Julia Vickerman for Cartoon Network that was released on its website on 18 May 2015.

In 2015, he provided the voice for a satirical anti-war film by the UK branch of Veterans for Peace called Action Man: Battlefield Casualties.

[citation needed] Berry provides the voice for the torture droid 8D8 in the 2021 Star Wars television series The Book of Boba Fett.

[citation needed] In 2023, Berry narrated a short segment in an episode of Last Week Tonight with John Oliver about freight trains titled ‘The Sad Tale of Henry the Engine’, a spoof on the Thomas & Friends television series.

[48] Berry wrote music for the BBC 2 Steve Coogan comedy Saxondale and appeared in the first and third episodes of the second series of the show.

[citation needed] Berry is friends with musical composer Dan McGrath and contributed to the Strictly Come Dancing theme song by playing guitar and providing the audible "Hey".

[51] Berry has recorded eleven studio albums: Jackpot (1995), Opium (self-released, 2008), Witchazel (2011), Kill the Wolf (2013), Music for Insomniacs (2014),[52][53] The Small Hours (2016),[54] Television Themes (2018), Phantom Birds (2020) and The Blue Elephant (2021).

In 2017, a "companion piece"[56] to The Small Hours was released, Night Terrors, featuring remixes by artists such as Saint Etienne.

Berry stated in the first issue of Bearded in 2007 that he was producing and collaborating on new material with 1960s soul singer Geno Washington and would record an album.

[citation needed] In October 2007, Berry provided a new track, "Cream Pie", to Bearded for readers to download free,[61] followed by a cover of the Blur song "Sing" in November 2007.