Matthew J. DelGuidice (born March 5, 1967) is an American former professional ice hockey goaltender.

DelGuidice started his career early, playing in Connecticut high schools, first for East Haven then on to Notre Dame, where he won the state title in his senior year.

DelGuidice played in the NCAA with St. Anselm College during the Hawks' 1986-87 season, and compiling a 13-11-3 record, and a .916 save percentage.

DelGuidice joined the University of Maine team, sitting out the 1987-88 season as the result of transferring.

In 1988-89, DelGuidice split playing time with Scott King, appearing in 20 games, with a 16-4-0 record, then going 3-1 in the post-season.

After his college career ended, DelGuidice went into the pro ranks with the Maine Mariners of the AHL for the 1990-91 season.

DelGuidice was called up to Boston, he played a game in relief for Andy Moog.

In 1991-92, DelGuidice became the back-up straight from training camp, he would get some net time with two stretches in Boston.

DelGuidice played for the San Diego Barracudas, New Jersey Rockin' Rollers, and Ottawa Loggers.