"[10][11] During the second overtime possession for the Seahawks, Hasselbeck threw an interception to Packers defensive back Al Harris which was returned 52 yards down the sideline for a touchdown.

[14] Upon returning he subsequently broke fingers on his non-throwing hand, but continued to lead his team to a 9–7 record and the divisional round of the post-season.

The fourth-seeded Seahawks defeated the Dallas Cowboys 21–20 in the wild card round in Seattle, then lost to the top-seeded Chicago Bears in overtime, 27–24.

Hasselbeck set career highs in yards, attempts, and touchdown passes in the 2007 season and was elected to his third Pro Bowl.

His bulging disk was diagnosed and treated with injections and he opened the regular season as the starter, but he hurt his knee after a hit early in the Seahawks' loss to the New York Giants on October 5.

"[18] In 2010, the season started off strong for Hasselbeck, leading his team to a 4–2 record and victories over the Chicago Bears and San Diego Chargers.

Seattle became the first team with a losing record to host a playoff game, taking on the defending Super Bowl XLIV champion New Orleans Saints during wild card weekend.

He threw for 272 yards, four touchdowns (a franchise postseason record) with one interception coming from a tipped ball, and a 113.03 passer rating, leading the Seahawks to victory over the Saints.

[21] In 2003, his first playoff appearance, Hasselbeck pronounced, "we want the ball and we're going to score" at the coin flip of overtime with the Green Bay Packers.

In 2005, Hasselbeck led the Seahawks to Super Bowl XL, where they lost to the Pittsburgh Steelers in a game remembered for its poor officiating.

Head referee Bill Leavy later apologized to Hasselbeck at a Seahawks offseason practice in 2010, publicly saying he would "go to his grave for kicking several calls in the fourth quarter that affected the outcome of the game.

"[25] In 2006, Hasselbeck rallied the Seahawks in the fourth quarter and threw the game-winning touchdown at Qwest Field to beat the Dallas Cowboys 21–20, but that occurred before Tony Romo's infamous dropped snap.

[26] In 2010, Hasselbeck led the Seahawks to a surprising playoff upset when he beat the New Orleans Saints, who were the defending Super Bowl XLIV champions and 11-point favorites.

Although the game would be remembered for Marshawn Lynch's Beast Quake run, Hasselbeck was an integral part in the win with 272 yards and four touchdowns.

However, the two sides had trouble reaching an agreement as Hasselbeck reportedly turned down a one-year offer before the NFL lockout began, asking for two years.

Hasselbeck was targeted by the Titans, who were looking for a veteran quarterback to help lead the team to wins while also mentoring first-round draft pick Jake Locker.

The Titans finished 2011 with a 9–7 record, narrowly missing out on the final playoff berth due to losing to the Cincinnati Bengals in Week 9.

[34][35] Hasselbeck's first action in the 2012 season came in Week 1 against the New England Patriots after Locker left early in the game with a shoulder injury.

[46] After a short week that included Hasselbeck being ill from a bacterial infection and having virtually no practice time, he was once again called upon to play for Luck.

On November 22, 2015, Hasselbeck started his third game for the Colts, as Luck suffered a kidney injury that would ultimately take him out for the remainder of the season.

However, injuries began to take their toll on the aging quarterback, and Hasselbeck's play would begin to deteriorate as the Colts lost three straight games.

Hasselbeck won the final start of his career, an 18–12 win over the Miami Dolphins, thanks in large part to Frank Gore's two rushing touchdowns.

[51] He and backup Charlie Whitehurst were unable to play the season finale due to injury; to take their place the Colts signed Josh Freeman and Ryan Lindley, who subsequently split time in a 30–24 win over the Titans.

[53] On March 9, 2016, Hasselbeck announced his retirement from professional football, and that he would join his brother Tim and become an analyst for ESPN, replacing Mike Ditka on Sunday NFL Countdown.