[1] Reis was traded to New England Revolution in January 2003 in exchange for Alex Pineda Chacón and a second-round pick in the 2003 MLS SuperDraft.

He became the first goalie in MLS history to stop two penalty kicks in one playoff game, doing as the Revs upset the much-favored Columbus Crew.

As an April Fools' Day prank in 2004, the Revs' front office announced their newest foreign acquisition, Luis "El Lobo" Fangoso, who eventually turned out to be Matt Reis wearing a shaggy wig and headband.

[5] Reis, who is bald, also convinced Mexican international José Manuel Abundis, who had just signed with the team, to shave his head for the 2006 MLS Playoffs.

On 15 April 2013, Reis was present at the Boston Marathon bombing where he saved the life of his father-in-law (John Odom), whose legs had been pierced by shrapnel, causing two severed arteries.