[3] Daddario attended the Collegiate School, before graduating with a degree in economics from Indiana University Bloomington[4] in 2010.

[6] In the same year he had a supporting role as Channing in the Vince Vaughn-led comedy film Delivery Man, directed by Ken Scott.

In 2014, Daddario portrayed Danny Ladouceur in the sports drama film When the Game Stands Tall, co-starring alongside Jim Caviezel, Laura Dern, and Alexander Ludwig.

The film is based on the achievements of football coach Bob Ladouceur and the De La Salle Spartans, who set a record 151-game winning streak.

[8] Also in 2016, he starred in the remake of Eli Roth's horror film Cabin Fever which was directed by Travis Z.