Matthew Nicholas (1594–1661) was an English Dean of St. Paul's Cathedral, London.
He was a younger brother of Sir Edward Nicholas, born on 26 September 1594.
He became rector of West Dean, Wiltshire, in 1621; of Broughton, Hampshire, in 1629; master of St. Nicholas hospital, Harnham, Salisbury, in 1630; prebendal rector of Wherwell, Hampshire, in 1637; vicar of Olveston, Gloucestershire, canon of Salisbury Cathedral and Dean of Bristol in 1639.
He died on 15 August 1661, and was buried at Winterbourne Earls, Wiltshire.
He was survived by two daughters and three sons (George, Edward and John) from the marriage;[1] one of the daughters, Elizabeth, married William Calley, and then as a widow in 1672 married Thomas Willis.