Pigasse himself has been active in the media business, selling Newsweb to Arnaud Lagardère, giving advice to Murdoch about Eurosport, helping Pink TV, as well as offering financial support to the pure player Rue89.

Since 2010, he has also become the co-owner along with Xavier Niel and Pierre Bergé of Le Monde, one of the main daily newspapers of France (politically, centre-left), as well as owner of the weekly magazine L’Obs (since 2014).

[2][3] In October 2018, staff at Le Monde learned that Pigasse had sold 49% of his stake in the company to Czech businessman Daniel Křetínský.

[7][8] Through his personal holding company LNEI, he acquired the music magazine Les Inrockuptibles in 2009 and Radio Nova in 2015.

[9] In 2016, he raised €250 million with Xavier Niel and Pierre-Antoine Capton to found Mediawan, a special purpose acquisition company (SPAC), with the ambition to become one of the largest media content and entertainment platforms in Europe.

A long-time Socialist Party member, he distanced himself from François Hollande's policies in 2014 through his third book Éloge de l’anormalité, in which he criticizes the inability of the elites globally to address the crisis and the systematic use of austerity measures.

In 2011 she writes an autofiction book about her husband's affair with the journalist Marie Drucker while she was pregnant with their third child.