Mattie V. Lee Home is a historic home located at Charleston, West Virginia.

It stands on what was once a densely packed commercial block close to the center of a historically African-American neighborhood in Charleston.

It was built about 1920 and is a two-story concrete block structure with a prominent raised basement and features a two-tier front porch.

[2] It was listed on the National Register of Historic Places in 1992.

This article about a property in Kanawha County, West Virginia on the National Register of Historic Places is a stub.