[1][2] Born in Portland, Oregon, Prickett often portrayed maids, aunts, secretaries, spinsters, busybodies, and nosy neighbors.

She played "Miss Tazey", Lois Lane's old nurse, in a 1952 episode of the Adventures of Superman.

She played Miss Sanders, a secretary to Howard McNear's character Wilbur Wilgus, on a 1959 episode of the ABC sitcom The Donna Reed Show.

Prickett also appeared in several episodes of The Andy Griffith Show as, variously, Mrs. Edna Larch and Aunt Nora, as well as in the role of Myrtle on Mayberry R.F.D.

Her final television performances were 1974 roles as Mabel on the CBS series Dirty Sally and as Mrs. Chandler on McMillan & Wife.