At a very young age, he moved to Bangalore for business purposes and settled in Madras in the year 1901.

For a particular period of time, he worked as an international business agent under Nawab C. Abdul Hakim.

[2][3] Due to his immense knowledge of the Quran and other Muslim religious scriptures, Sait was often called "Maulana".

[5] On his return from jail in 1923, he resigned from the Congress and founded the Madras Province Muslim League.

[1] This move was prompted by Sait's preference for Dominion Status when the Congress declaration of independence as its primary goal.

[7][8] A little before the 1937 elections, Sait, left the Madras Provincial Muslim League and joined the Indian National Congress.

In March 1940, a few months after resigning as Minister, Sait suffered chest pains and had to be hospitalized.

[11] During his campaigning for the Indian National Congress, Sait was accused of disrespecting Islam at a meeting in Coimbatore by not standing while verses from the Quran were read.