Maun Airport serves as the main gateway to the Okavango Delta and the Moremi Game Reserve.

Many tour operators offer chartered flights over the Delta and to Botswana destinations such as the Makgadikgadi Pans, one of the largest seasonal wetlands in Africa.

These operations, during their peak in the June to August high season, make the airport the second-busiest in Africa for aircraft movements.

[6] The aircraft were awaited as they brought news of the outside world, mail, medicines, foodstuffs, and above all, new people to a community hundreds of kilometres from the nearest big town.

The earliest known flights over the Okavango took place in July 1925, and were part of a survey of rivers in the region, using aircraft based in Livingstone.