Mauritius sent a delegation to compete at the 2016 Summer Paralympics in Rio de Janeiro, Brazil, from 7–18 September 2016.

The Mauritian delegation to Rio de Janeiro consisted of two athletes: wheelchair racer Brandy Perrine and short-distance swimmer Scody Victor.

The nation's best result was tenth overall by Perrine in the women's 100 metres T54 event as both competitors did not progress to the final in their respective competitions.

[2] The country sent a delegation of two athletes to Rio de Janeiro: wheelchair racer Brandy Perrine and short-distance swimmer Scody Victor.

[3] They were joined by chef de mission Reynolds Permal and coaches Sanjay Bookun and Édouard Ah Piang.

[12] Victor said before the Paralympics that he was happy to be in Rio de Janeiro and stated that he did not put pressure on himself, "I have lowered the pace of my training since yesterday, so I can recover enough for the competition.