The university offers bachelor's and master's degree programs in liberal arts and sciences.

The site of the college was located at about four miles away from the north east of the downtown section of Moulmein (Mawlamyine).

About a quarter of a mile away from the college across the Moulmein-Taungwaing road, there was a former WWII airfield (now Mawlamyine Airport) used by the Royal Air Force and the American Flying Tigers.

On 14 June 2018, State Counsellor Aung San Suu Kyi and youths from the Mon, Karen and Pa’oh ethnic groups held a conference at Mawlamyine University.

[7] University entrance to a particular undergraduate degree program derives from students' tenth grade standard examination marks.

The Ministry of Education (Myanmar) runs the matriculation exams, which occur at the same time annually around country.

Its Marine Science Laboratory in Setse, a coastal town about 83 km south of Mawlamyine was the first of its kind in Myanmar.

Currently, there are five halls of residence in the campus; namely Thandar, Mawlamyine (Moulmein), Nilar (Sapphire), Pu-le (Pearl) and Shwe Myaing building.

Others are identified with particular academic disciplines such as physics, chemistry, and mathematics known as course-related organizations, and still others belong to the special or interest groups.