[13] Hocane made her Hindi film debut with the romantic tragedy Sanam Teri Kasam opposite Harshvardhan Rane.

"[17][18] In 2018, she made her Pakistani film debut with the romantic comedy Jawani Phir Nahi Ani 2 opposite Fahad Mustafa.

Pakistan Today noted, "Mawra is a good addition to the film and she nailed her character of a spoilt, young heiress.

[23] Her next role of a headstrong and ambitious university student in Sabaat earned her dual nominations of Best TV Actress at 20th Lux Style Awards.

[24] In 2021, she played title role of a victim of domestic abuse and marital rape in Qissa Meherbano Ka.

[27] She later appeared as an innocent teen Rishtina who discovers the world after spending twenty years of her life in a basement in Kashmiri's directed Nauroz.

[28] Hocane had her first role in 2024 in the comedy Let's Try Mohabbat, where she portrayed a newlywed bride who changes the perspectives of her in-laws with her arrival.

[38] Hocane once tweeted about the Indian film Phantom, which was banned in Pakistan, prompting social media harassment.