The origins of the city date back to 1757 in Spanish Cuba,[1] when the first farms were established here by immigrant colonists.

The municipality is divided into the barrios and hamlets of Barajagua, Cabonico, Cajimaya, Chavaleta Norte, Chavaleta Sur, Guayabo, Juan Vicente, Mateo Sánchez, Punta de Tabaco, Río Frío, Sae-Tía, San Gregario Norte, San Gregorio Sur and Santa Isabel.

[4][5] Among other barrios or neighborhoods in this municipality are: Felton (on Cajimaya Bay, once the seaport for the Bethlehem Cuba Iron Mines Company -Bethlehem Steel-), Guaro, Guatemala (on Nipe Bay, previously named Preston and a central sugar mill operated by the United Fruit Company), Nicaro-Levisa (on Levisa Bay, originally named Lengua de Pajaro which translated into English means bird's tongue -as viewed from an air ride-), El Purio, Santa Rita, La Italiana, Mandinga.

The last two being on the road to the open mines named Mina Martí where nickel and cobalt exploitation started in the beginnings of the twentieth century by Bethlehem Cuba Iron Mines Company (Bethlehem Steel) and Nicaro Nickel Company.

[7] Other attractions include Cayo Saetía, a scenic cay with beaches located within the municipality on the Bay of Nipe, north of the Mayarí city.