Mayes Castillero Rubeo (born 1962) is a Mexican costume designer.

She is known for her work on the films Apocalypto (2006), Avatar (2009), John Carter (2012), World War Z (2013), Warcraft (2016), Thor: Ragnarok (2017) and Jojo Rabbit (2019), the lattermost of which earned her Academy Award and BAFTA Award nominations.

After graduating, she moved to Italy to work with Italian Costume Designer Enrico Sabbatini.

Three years later she worked with James Cameron on Avatar, for which she was nominated for the Costume Designers Guild Award in the Excellence in Fantasy Film category.

[2] She received the Artistry in Filmmaking Award at the 2021 Coronado Island Film Festival.