Mayfair is a historic home located near Jenkinsville, Fairfield County, South Carolina.

It was built about 1824, and is a two-story, weatherboarded Federal style frame residence with a hipped roof.

The front façade features a central, two-story, polygonal pedimented portico.

According to local tradition, Mayfair was the home of Burrell B. Cook, a moderately wealthy planter, who served in the Twenty-eighth General Assembly of South Carolina from 1828 to 1829.

This article about a property in Fairfield County, South Carolina on the National Register of Historic Places is a stub.