Mayfield Cottage is a historic plantation house located near the grounds of Central State Hospital near Petersburg, Dinwiddie County, Virginia.

[4] Built about 1750, the 1+1⁄2-story brick Colonial era mansion features a jerkin-head roof, distinctive interior woodwork, and classic Virginia style Flemish bond masonry.

[5] Shortly after the American Revolutionary War, William Digges Sr. lived at Mayfield and advertised for overseers for his Denbigh Plantation downstream in Warwick County (which near Yorktown was damaged during that conflict).

In 1882, Henry Chamberlayne Willson and his wife Eliza sold the house and 290 acres including a granite quarry to the city of Petersburg.

In accordance with special legislation passed by the Virginia General Assembly, it was accepted by the board of trustees of the Central Lunatic Asylum as the site of their future hospital.