The Mayo Building at the northwest corner of West Fifth Street and South Main St. in Tulsa, Oklahoma was built in 1910.

"[3] The Mayo Brothers, who had established a thriving furniture business in 1904, had already moved to a larger rented building on Main Street in 1906, then decided they needed still more space, which they began constructing at 420 South Main in 1909.

They used half the space for their own business and rented the rest of the building as offices for oil companies.

As the demand for office space increased, the Mayos built an identical five-story building at 418 South Main in 1914.

[5] It was identified as one of the supporting structures during the creation of the Oil Capital Historic District.