Mayobridge (from Irish Droichead Mhaigh Eo 'bridge on the plain of yews') is a village within County Down, Northern Ireland.

It lies on the small river Clanrye, which divides the townlands of Mayo and Bavan, 4.4 miles (7.1 km) east of Newry.

Mayobridge is classified as a small village or hamlet by the NI Statistics and Research Agency (NISRA).

[1] On 15 August 1859, Dr. Leahy, the co-adjutor bishop of the diocese, blessed the foundation stone of a new Catholic church to replace the existing, more primitive Mass House put up in 1806 (parts of which are still visible in the disused Parochial Hall); and a curate was appointed to live in Mayobridge.

The minutes of the Central Council of the GAA record that, on 30 April 1888, an application for affiliation was received from St Patrick's, Mayobridge.