This is a list of mayors and chiefs of government of the city of Buenos Aires, Argentina's capital, since its federalization.

Its first Mayor (Spanish: Intendente, Intendant) was Torcuato de Alvear, who was appointed by President Julio Argentino Roca following the city's federalization.

For the next 110 years, the intendant was directly appointed by the president, meaning that Buenos Aires had less autonomy than the smallest municipality.

In 2006, Chief Aníbal Ibarra was removed from his position following impeachment regarding the Cromagnon nightclub tragedy, leaving Vice-Chief Jorge Telerman to take over the office.

Horacio Rodríguez Larreta became mayor in 2015, after defeating Michetti in the primary elections and Martín Lousteau in a ballotage.