In 1966, as a college student she appeared in the William Grefé-directed "B"-movie The Death Curse of Tartu, under the stage name Mayra Christine.
In 1976, when the successful Televisión Española game show Un, dos, tres... responda otra vez returned to television to be broadcast in color for the first time, Mayra auditioned for the role of one of the secretaries on the program.
That year, Mayra teamed with two of the show's former secretaries, María Durán and Beatriz Escudero, to form the pop vocal band Trío Acuario (Aquarius Trio because that was the zodiac sign of all three women).
Mayra left the group in 1978 to pursue a solo career, recording the album Una Dama (One Lady), which included her cover of Julio Ramos's anti-abortion pop hit "No Te Dejan Nacer" ("They Won't Let You Be Born").
She left Dabadabada in 1982 when she was chosen by Chicho Ibáñez Serrador as a substitute for Kiko Ledgard, the famous host of Un, dos, tres... responda otra vez, who had suffered a near-fatal accident.
She made contributions to Menta y Chocolate (Antena 3 TV), Salsa Rosa, Dolce Vita, A Tu Lado and TNT (Telecinco).
At the end of 2006, she appeared on the second season of the stand-up contest show El Club de Flo (LaSexta), winning second place.
Over the course of a year, with the help of speech therapists and specialists, she completely regained her ability to speak, albeit with a slightly affected pronunciation as an after effect of the operation.