Mazanovo (Russian: Мазаново) is a rural locality (a selo) in Mazanovsky Selsoviet of Mazanovsky District, Amur Oblast, Russia.

Mazanovo is located on the left bank of the Zeya River, 8 km west of Novokiyevsky Uval (the district's administrative centre) by road.

Beloyarovo is the nearest rural locality.

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