[3] Mazosia is a genus of crustose lichens, meaning it forms a thin, crust-like layer that adheres tightly to the surface it grows on.

The photosynthetic partner, or photobiont, is typically from the genus Trentepohlia, with cells that are round to oval (7–17 μm wide) and either occur singly or form short chains.

[4] In cross-section, the proper exciple has a cup-like shape and is made of vertically oriented hyphae (fungal filaments) that are 3–6 μm thick, red-brown to carbonised (blackened) in colour, and turn olive-green when treated with K. The layer beneath the hymenium, or hypothecium, is pale brown to colourless.

The hymenium (the spore-producing layer) is clear, not filled with oil droplets, and shows a faint blue reaction when treated with iodine-based stain (hemiamyloid).

Mazosia also produces asexual spores in structures called pycnidia, which can be either embedded within the thallus or slightly protruding.