McArdle Laboratory

Founding faculty Harold P. Rusch, Roswell Boutwell, Charles Heidelberger, Elizabeth and James Miller, Gerald C. Mueller, and Van Rensselaer Potter helped to establish the international reputation of the McArdle Laboratory and to build the strong foundation of basic cancer research on the University of Wisconsin campus.

Howard M. Temin (1934-1994) received the Nobel Prize in Physiology or Medicine (shared with David Baltimore and Renato Dulbecco) in 1975 while a member of the faculty at the McArdle Laboratory.

McArdle alum Günter Blobel received the Nobel Prize in Physiology or Medicine in 1999 for "the discovery that proteins have intrinsic signals that govern their transport and localization in the cell".

The foundation for the development of the Laboratory and the University of Wisconsin's program in experimental cancer research was made possible by the generous donations of private citizens.

One of the Bowman Fellows, Harold P. Rusch, became the first Director of the McArdle Laboratory and established the cancer research program at the University of Wisconsin.

Expanded facilities, funded by the National Cancer Institute, were provided by the construction in 1964 of the McArdle Laboratory building in the center of the UW-Madison campus.

McArdle scientists established the basis of the chemical induction of various cancers and discovered how known carcinogens initiate the genetic changes in cells that result in tumor formation.