McKendree Mitchell House is a historic home located at Batesburg-Leesville, Lexington County, South Carolina.

It was built in 1873, and is a 1+1⁄2-story, Greek Revival style cottage on a brick foundation.

It is sheathed in weatherboard and features a projecting central gabled portico.

[2][3] It was listed on the National Register of Historic Places in 1982.

This article about a property in Lexington County, South Carolina on the National Register of Historic Places is a stub.