[3] It is in the valley of the Nenana River along the eastern edge of Denali National Park and Preserve.

The George Parks Highway (Alaska Route 3) is the main road through the CDP: Anchorage is 231 miles (372 km) to the south, and Fairbanks is 128 miles (206 km) to the north.

Denali Park has a subarctic climate (Dfc) like most of Alaska.

Winters are severely cold with extremely heavy annual snowfall averaging 76.7 inches (195 cm).

Most of Denali Park's precipitation occurs during the months of June - September.

41.7% of all households were made up of individuals, and 1.4% had someone living alone who was 65 years of age or older.