The Michael G. DeGroote Centre for Learning and Discovery, which houses the faculty's medical school also houses more than 250 scientists and McMaster's medical institutes including, the Centre for Function Genomics, Centre for Gene Therapeutics, Institute for Cancer and Stem Cell Biology Research, Robert E. Fitzhenry Vector Laboratory, Centre for Asthma and Allergy Research (Allergen), the Michael G. DeGroote Institute for Pain Research and Care and North American Headquarters for West Nile studies.

[15] The campus in St. Catharines is located at Brock University's Niagara Health and Bioscience Research Complex.

Offers of admission to the medical school are made from a rank list irrespective of geographical preference.

[21] In the field of clinical medicine and pharmacy, the ARWU in 2010 ranked the program 51st–75th in the world and third in Canada.

[24] For five years in a row, McMaster has ranked second in Canada for biomedical and health care research revenues.

Researchers there have identified differences in his brain that may relate to his genius for spatial and mathematical thinking.