The McNab was bred to withstand the tough conditions found in California such as heat, burrs, foxtails, and rugged terrain.

The MSR is what is known as a "founding registry" because they exclusively utilize discovered genetic markers and DNA verification for registration.

Beginning in 2014, the MSR worked with Mars Veterinary on a study in an attempt to establish a unique genetic signature for the McNab Shepherd.

Additionally, the tested dogs were also evaluated for certain physical traits and over 100 disease-causing mutations to help establish a baseline for these in the McNab population.

A working McNab frequently runs for miles a day, using its herding skills to control livestock, and they can become restless if isolated or neglected.

Providing a McNab has plenty of exercise, it is content to nap at its owner's side with a watchful and protective eye.

McNab dogs may carry the MDR1 mutant gene and can be very sensitive to Ivermectin, which is a common ingredient in heartworm prevention medications.

[4] A DNA test that demonstrates whether a dog has the mutation is available through the Washington State University College of Veterinary Medicine.

In addition to the above activities, McNabs are now becoming more common as service dogs, demonstrating sensitivity to the medical and psychological needs of humans.

Alexander McNab left his native Scotland in the late 19th century, homesteading his 10,000 acre sheep ranch located in the Sanel Rancho, which later became Hopland, California.

Refinement of the McNab Shepherd continued and additional dogs were imported from Scotland for breeding and ranching purposes.