[1] The song is about Wainwright's relationship with Liza Minnelli, who was reportedly upset by his 2006 tribute concerts to her mother, Judy Garland.

[5] As a driving bass line emerges, lyrically Wainwright references his father's "connection" to Minnelli years ago.

Whiteway noted that "Rufus leaves it until the final lines of the song to correct the inherent syntax errors, singing "Liza and I" as his iconic vocals fade out.

"[5] On January 12, 2014, BBC Radio 2's Weekend Wogan premiered "Me and Liza", the lead single for Vibrate: The Best of Rufus Wainwright.

[23][24] Clash's Robin Murray called "Me and Liza" a "glamorous show tune, harking back to the glory days of the West End".

[25] Contactmusic.com said the song "kicks off with an understated almost bare driving beat before Rufus's trademark vocal comes sweeping over the top, building into a sumptuous, soaring chorus and climactic end".

[26] Gigwise's Andrew Trendell wrote that the track has an "addictive bassline and confident swagger", and categorized it as one of the "poppier tones" on the album.

[28] David Whiteway of Renowned for Sound awarded "Me and Liza" four out of five stars and said that, "set amongst the cream of his 16 year, 7 studio album career", the song could "reaffirm [Wainwright's] status as one of the great songwriters of his generation.

[31] The following week, Wainwright's rank on the chart increased by eight positions to number 12; he was named the "hot shooter" for having the greatest leap.