The film tells the story of jaunty young policeman Danny Dolan (Tracy), who falls in love with waterfront cafe waitress Helen Riley (Bennett).

According to TCM, it did well with critics and audiences, featuring fine performances from its two stars, "displaying the superb chemistry" that can be seen in their other pictures together.

Danny has a soft spot for Helen Riley, a sharp-tongued waitress at a cheap diner, while her scatterbrained sister, Kate, is in love with Duke, a sleazy low-level mobster.

Bennett and Tracy made She Wanted a Millionaire that year, with their billing reversed (Bennett billed over Tracy), and also played a married couple two decades later in Father of the Bride and Father's Little Dividend.

Me and My Gal was remade as a B film in 1940 by Fox as Pier 13, directed by Eugene Forde.