Lobo recalls: "I was working on several songs, including a tune about traveling around the country with this girl, and I was trying to rhyme 'you and me.'

I was thinking about it, sitting in a room that had a big sliding glass door overlooking the back yard.

My big German Shepherd dog: Boo, came running around the corner and looked in at me.

I hadn’t been to any of the places mentioned in the song except Georgia, but I just kept putting in places that sounded far away like Minneapolis and L.A."[4] The single peaked at number 5 on the Hot 100 and was the first of four of his songs to hit number 1 on the Easy Listening chart, where it had a two-week stay at that top spot in May 1971.

[7] Internationally, "Me and You and a Dog Named Boo" was Lobo's second most successful song among more than 15 single releases, surpassed only by "I'd Love You to Want Me" the following year.